Despite major advances in biomedical science, effective treatment of complex diseases such as cancer, neurodegenerative disorders, and chronic inflammatory conditions remains limited by the inability of traditional therapies to overcome biological barriers, achieve precise targeting, and minimize off-target effects. Conventional therapies and drug delivery systems often lack specificity, leading to suboptimal therapeutic outcomes, systemic toxicity, and reduced patient quality of life. The Fetse Lab addresses these challenges through an integrated research program focused on peptide-based modulation of protein–protein interactions, targeted drug and gene delivery systems, and biomaterial platforms for minimally invasive or non-invasive therapies.

Our lab develops peptide-based delivery platforms that improve the transport of a broad range of therapeutic payloads, including mRNA, siRNA, gene-editing tools, proteins, and small molecules.

Targeting protein-protein interactions (PPIs) remains one of the biggest challenges in drug discovery. Antibodies, while highly specific, are often limited by poor tissue penetration, high production costs, and an inability to access intracellular targets.

Improving patient compliance in therapy requires developing minimally invasive and non-invasive drug delivery systems that enhance drug transport while minimizing discomfort, procedural risks and recovery time.
Fetse Lab
96 Corliss Ave, Johnson City, NY 13790, USA
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