The Fetse Lab focuses on developing next-generation therapeutics at the interface of peptide drug discovery, biomaterials, and nanocarrier design. Our work centers on engineering peptide-based modulators of protein–protein interactions, building targeted drug and gene delivery systems, and designing minimally invasive platforms that bypass biological barriers. We apply these technologies to address unmet needs in cancer, neurodegenerative diseases, and chronic inflammatory conditions, with the goal of improving therapeutic precision, safety, and accessibility.
In our lab, we design therapeutic peptides, peptidomimetics, and peptide-functionalized delivery systems that can precisely engage disease-relevant pathways and improve the transport of small molecules, proteins, and nucleic acids. By combining molecular design, phage display, materials engineering, and AI-guided optimization, we’re working to build safer, more effective, and accessible therapeutic platforms that address real clinical challenges.
We take a collaborative, problem-driven approach to therapeutic discovery, drawing from chemistry, biology, and materials science. The Fetse Lab is committed to advancing fundamental and mechanistic insights that drive the development of innovative, translatable therapies with broad impact across cancer, neurodegenerative, and inflammatory diseases.